Berikut keterangan obat tersebut:
Rhinos® SR
Sustained release capsules
Box, 5 blisters @ 10 capsules
ON MEDICAL PRESCRIPTION ONLY
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Composition:
Each capsule contains:
- Immediate release
- Loratadine 5 mg
- Pseudoephedrine HCl 60 mg
- Sustained release
- Pseudoephedrine HCl 60 mg
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Pharmacology
- Loratadine is a potent long-acting tricyclic antihistamine with selective peripheral H1-receptor antagonistic activity.
- Pseudoephedrine (d-isoephedrine) is a stereoisomer of ephedrine which is a sympathomimetic agent with direct effects on adrenergic receptors which give decongestant effect.
- In a sustained release capsule, pseudoephedrine may exert its effects for at least 12 hours.
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Indications
Relief of symptoms associated with allergic rhinitis, such as sneezing, nasal congestion, rhinorrhea and nasal pruritus. This drug is recommended when both of antihistaminic effect of loratadine and decongestant effect of pseudoephedrine are needed.
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Contraindications
-
Sympathomimetic agents are contraindicated in patients with cardiovascular diseases such as coronary insufficiency, arrhythmia and severe hypertension.
- Patients receiving monoamine oxidase (MAO) inhibitor therapy or within 10 days of discontinuing such treatment and in patients with narrow-angle glaucoma, urinary retention, severe hypertension, severe coronary artery disease and hyperthyroidism.
- Hypersensitivity to pseudoephedrine and loratadine.
- Administration concomitantly with ketokonazole and azole derivates or macrolide group.
- Respiratory failure.
- Patients who have shown hypersensitivity or idiosyncrasy to their components, to adrenergic agents or to other drugs of similar chemical structure.
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Dosage and Administration
Adults and children 12 years of age and over: 1 capsule every 12 hours.
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